TetraQ has GLP recognition for the conduct of both in vitro and in vivo toxicology services and has experience in undertaking complete preclinical study packages for inclusion in investigational new drug applications (INDs).
TetraQ runs all rodent toxicology studies in house, and collaborates with external providers to provide streamlined packages which can include rabbits or dog. If you have a particular species you are interested in using please contact us for further information as to the service we can provide.
Dosing regimens via intravenous, oral, subcutaneous, intraperitoneal or intramuscular routes can be accommodated as well as multiple dosing per day as required.
The customised client package can also make use of the state of the art TetraQ bioanalytical facilities to provide screening assays right through to drug and metabolite analysis methods fully validated using the species and biological matrix of interest.
Our GLP Toxicology services include:
- Acute Dose Toxicity Studies
- Repeat Dose Toxicity Studies
- Safety pharmacology
- Genotoxicity assays (AMES, MLA, Micronucleus)
- Cytotoxicity Assessments
- Toxicity Screening
- Stability Testing
- Toxicokinetic analysis