Quality assured preclinical & clinical testing solutions

Capabilities Overview

ADME/Bioanalytical

  • Bioanalytical method development &  validation of LC-MS, GC-MS, Elisa
  • Sample analysis (Animal, Human)
  • Animal PK & TK studies
  • Metabolic Stability (Microsomes, hepatocytes, S9
  • Metabolite ID (Lightsight software)
  • Biodistribution studies
  • Plasma protein binding
  • Bioanalytical & PK support for human trials
  • WinNonlin Phoneix validated
  • State of Art Instrumentation

 

Toxicology

  • Genotoxicity
  • Acute & Repeat Dose Tox Studies
  • Safety Pharmacology
  • hERG, Respiratory and CNS
  • Cytotoxicity Screening
  • Provantis (GLP Data Mgt) validated

 

Pharmaceutics

  • Formulation
  • Stability trials & stability indicating method development
  • Physicochemical Profiling
  • Dissolution studies
  • Caco-2 Cell Studies
  • Solubility studies

 

R&D of Methods & Toolkits

  •  Disease Models Development
  •  Bioanalytical Methods Development
  •  Other Methods

 

Efficacy

  • Specialist expertise in Pain: nociceptive, inflammatory, neuropathic (14 validated models)
  • Arthritis – CAIA in the mouse
  • Multiple Sclerosis
  • Obesity
  • Diabetes
  • Burrowing Test
  • Respiratory Depression
  • Constipation
  • Sedation, motor impairment
  • Ex-vivo mode of action studie

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TetraQ Capabilities

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Technical infrastructure

Information about the laboratories and technical infrastructure More...

REACH

TetraQ has experience in supporting clients to meet the REACH requirements More...

Quality System

TetraQ operates within a quality framework in compliance with international standards More...

Fact Sheets

TetraQ Capabilities

Overview of Capabilities and Services

More...

TetraQ - Birds Eye View

A one-page overview of TetraQs services and capabilities

More...
All Factsheets